Course: General Pharmacology

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Course title General Pharmacology
Course code KBBV/C401
Organizational form of instruction Lecture
Level of course Master
Year of study not specified
Semester Summer
Number of ECTS credits 3
Language of instruction Czech
Status of course Compulsory-optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Šiller Michal, Mgr. Ph.D.
  • Brůčková Lenka, Mgr. Ph.D.
Course content
General Pharmacology T l: Introduction (branches and scope of the subject of discipline and relation with other medical fields, definitions, drug nomenclature) T 2: Pharmacodynamics I ( specific and unspecific drug action, receptors and transduction mechanisms) T 3: Pharmacodynamics II (pharmacodynamic interactions, mediators and local hormones) T 4: Pharmacokinetics I (membrane transport mechanims, absorption and distribution, volume of distribution) T 5: Pharmacokinetics II (drug biotransformation and excretion) T 6: Pharmacokinetics III (pharmacokinetic concepts of bioavailability, half life, clearance etc.) T 7: Factors influencing pharmacokinetics and pharmacodynamics (modes of drug administration, drug and dosage forms etc.) T 8: Pharmacogenomics/-genetics in drug action (variables of functional dynamics) T 9: Development of new drugs (drug discovery processes, pre-clinical evaluation) T 10: Clinical drug evaluation (designing and ethics of trials, medicolegal aspects) T 11: Pharmacovigilance (principles of activities in ARDs monitoring) T 12: Drug toxicity (basic principles, management of intoxications) T 13: Actuality and perspectives (cannabinoid system in the brain) T 14: Tutorial discussion class

Learning activities and teaching methods
unspecified, Dialogic (discussion, interview, brainstorming), Projection
Learning outcomes
In this course students will be trained to know and explain the general principles of pharmacology (1st section of study) and systemic pharmacology (2st section of study).
The graduate should be able to act as a productive member of a team enganged in research development and distribution of pharmaceuticals. He should be able to utilize the acquired skills in research and industry, as well as in planning and organizazion of projects with a view to health matters.
Prerequisites
Examination in physiology.

Assessment methods and criteria
Oral examination, Didactic test

control knowledge test and final oral examination
Recommended literature
  • Květina, Jaroslav. Základy farmakologie.. Brno: Veterinární a farmaceutická univerzita, 1999. ISBN 80-85114-44-5.
  • Martínková, Jiřina. Farmakologie pro studenty zdravotnických oborů. Praha: Grada, 2007. ISBN 978-80-247-1356-4.


Study plans that include the course
Faculty Study plan (Version) Branch of study Category Recommended year of study Recommended semester
Faculty of Chemical Technology Analysis of Biological Materials (2016) Special and interdisciplinary fields 1 Summer
Faculty of Chemical Technology Analysis of Biological Materials (2015) Special and interdisciplinary fields 1 Summer
Faculty of Chemical Technology Analysis of Biological Materials (2013) Special and interdisciplinary fields 1 Summer